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Weight loss remains the cornerstone of OSA management, but pharmacologic agents that induce significant weight loss and potentially modulate central respiratory pathways may offer added benefit (Figs

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Medical Management of Obesity: A Comprehensive Review of FDA-Approved and Investigational Therapies

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It has also shown beneficial effects in rats with various gastrointestinal anastomoses, even when impaired with the application of NSAIDs, cysteamine, large bowel resection, and other conditions